researchers have revealed the crucial role of a protein

researchers have revealed the crucial role of a protein

It is a hopeful discovery for women, in the fight against breast cancer. Researchers have discovered that a protein plays a crucial role in the development of metastases linked to aggressive breast cancer. And according to them, targeting this protein would increase the life expectancy of patients.

So-called “aggressive” breast cancers are types of cancer that spread quickly. These types of cancers, such as triple-negative, which represent 10 to 20% of breast cancers, are very difficult to treat. However, according to the study led by the CNRS, and published this Wednesday in the scientific journal Cell Discoverythe protein responsible for the multiplication of cancer cells is the protein SMYD2.

So-called “aggressive” breast cancers are types of cancer that spread quickly. These types of cancers, such as triple-negative, which represent 10 to 20% of breast cancers, are very difficult to treat. However, according to the study led by the CNRS, and published this Wednesday in the scientific journal Cell Discoverythe protein responsible for the multiplication of cancer cells is the protein SMYD2.

“Up to 10 times fewer metastases”

The Franco-American team of scientists, who researched mice suffering from mammary cancer at the primary stage, has also highlighted a correlation between the inhibition of this SMYD2 protein and the appearance of metastases. “We saw up to 10 times fewer metastases developing in the organs around breast cancer in these mice,” explained to our colleagues atEurope 1 Nicolas Reynoird, CNRS researcher at the University of Grenoble.

According to the CNRS, these results represent a “promising first step” towards the development of an early therapy preventing the development of metastases. Such preventive treatment would give the medical team more time to identify and implement an effective therapy against the primary tumor, or find an alternative for refractory tumors, he explains.



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