Loire. Volunteers called to participate in a study on long Covid

Loire.  Volunteers called to participate in a study on long Covid


They caught Covid, suffered acute symptoms, and still have not recovered.

Four years after the start of the Covid-19 pandemic, patients are still suffering from symptoms after being infected with SARS-CoV-2 (severe fatigue, neurological disorders, cardio-thoracic disorders, digestive, skin disorders), which of this long Covid a complex disease difficult to diagnose.

“Almost 10% of the population who contracted the disease could be affected by long Covid,” estimates Caroline Dupré, research engineer, head of the monitoring and adapted pathway project for people suffering from persistent Covid-19 symptoms (SPACO +). A project, or rather a study undertaken, since the end of 2023, to improve the quality of life of this public thanks to a personalized intervention.

If around twenty volunteers presenting persistent clinical signs of Covid-19 for more than twelve weeks have already been recruited to participate in this research work, the study plans to include a total of 270 in France and 130 in Cameroon.

Why Cameroon? “The project, funded by the National Agency for Research on AIDS and Hepatitis (ANRS), is supported by the Saint-Etienne University Hospital, the Presage Institute of Jean-Monnet University and also the universities of Douala and Yaoundé in Cameroon,” relates the engineer.

One group will benefit from workshops, the other from health recommendations

Once the candidate’s profile meets the inclusion criteria, being over 18 years old, suffering from persistent symptoms of Covid validated by their doctor, being affiliated to or entitled to a Social Security scheme, the volunteer is invited to meet the clinical research associate who will present the research work to him, will carefully check the inclusion criteria, and will arrange a first appointment with a nurse at the Regional Institute of Sports Medicine and Engineering (Irmis) .

Privileged contact throughout this work, she will carry out an initial assessment of the patient before integrating him into one of the two groups. The first, called “intervention”, will benefit from three months of workshops.

Workshops set up by a national association bringing together patients with long Covid to alleviate these often disabling symptoms. They will be led by the research associate, the nurse who follows them, a neuropsychiatrist, an occupational physician. The other group, called “control”, will follow a standard of care.

“He will also be evaluated and will meet three times with nurses who will provide the recommendations of the High Health Authority and the tools used during the workshops. They can also be referred to other ongoing studies,” explains Caroline Dupré.

“The objective is to demonstrate the interest of the workshops offered with a positive impact on the quality of life of patients. We also hope for the volunteers in the control group, an improvement in their quality of life which would show that being followed by someone also helps. »

Publication of the results of the study is planned for the end of 2025.

Contact: or [email protected]. No compensation for volunteers.


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