From milk thistle to green tea, from broccoli to tomato, up to horse chestnut: the seven substances at the basis of the new supplement studied by the experts of the Italian Society of Andrology (SIA) to take care of men’s health come from nature. The mix of substances is the result of collaboration between researchers from SIA, the first Italian scientific society to have developed a nutraceutical, and the Institute of Clinical Pharmacology of the University of Catanzaro.
The supplement is called droxane and will be on the market from next July. The idea is to give support to all healthy men who want to take care of their health, not only sexual health, thanks to beneficial effects that have been documented by a recent review of the studies on the seven substances included in the supplement, published in the journal scientific Uro.
In fact, research has shown that thanks to its powerful antioxidant and anti-inflammatory activity, the new mix based on silymarin, sulforaphane, lycopene, escin, green tea, reduced glutathione and tryptophan is able to contribute to the prevention of some tumors such as prostate cancer. and reduce the urinary symptoms of benign prostatic hypertrophy, but also improve the cardiovascular risk profile, liver activity and mood.
by Elvira Naselli
“Aging, an incorrect lifestyle and exposure to environmental pollution are elements that can compromise health, largely because they induce an increase in the production of free radicals and greater oxidative stress which damages cells and tissues, leveling the road to tumors, metabolic and cardiovascular diseases – he explains Alessandro Palmieripresident of SIA and professor of Urology at the Federico II University of Naples -. Correct nutrition is essential to combat these phenomena and is the basis for health and well-being, but there are bioactive molecules that can be of great help because they are capable of improve biological functions”.
by Daniele Banfi
The Italian Society of Andrologists is the first Italian scientific society to have developed a nutraceutical. “The experts of the Italian Society of Andrology (SIA), thanks to the SIA Benefit Community spin-off created to create new health opportunities, have isolated the seven best bioactive molecules with specific and documented positive actions such as antioxidants and anti-inflammatory, creating a mix, Drolessano, in which they are found in high concentrations so as to become a valid support for men’s health”, he comments Fabrizio Palumboproject manager and Medical Director at the UOC Urology Ospedale Di Venere in Bari.
The seven constituents of the new supplement are silymarin, sulforaphane, lycopene, escin, green tea, reduced glutathione and tryptophan. “They were chosen not only because they have beneficial effects on the body regardless of age and health conditions, but also because they have no side effects and can be included in a single supplement without giving rise to negative interactions, but rather mutually enhancing their positive actions,” he explains Luca Gallelli, of the Institute of Clinical Pharmacology of the University of Catanzaro.
These compounds are mainly extracted from plants known for their healing abilities: sulforaphane, for example, is extracted from cruciferous vegetables such as broccoli, Brussels sprouts and cabbage and is an excellent antioxidant and anti-inflammatory that has been shown to inhibit the growth of cancer cells .
Lycopene from tomatoes is a carotenoid with similar properties that studies indicate can protect against prostate cancer and help treat the symptoms of benign prostatic hypertrophy. The recent review published by SIA experts and pharmacologists of the University of Catanzaro in the journal Uro, which took stock of the documented effects of the seven compounds present in Drolessane, also underlined the antioxidant capacity of glutathione, the positive action on mood and cognitive activity of the amino acid tryptophan and the many benefits of green tea, which protects against the toxicity of many carcinogens and has been shown to contribute to the prevention of tumors.
by Valentina Arcovio
“In Drolexane we also included two compounds whose specific positive action for male health has been verified – he adds Thomas Caiurologist at the S. Chiara Hospital in Trento – it is escin extracted from the seeds and shell of the horse chestnut, a powerful antioxidant useful in the field of urolithiasis, male infertility and varicocele, prostate cancer and bladder, chronic prostatitis: the data show among other things a possible anti-tumor effect in prostate cancer cells and an anti-inflammatory activity comparable to that of cortisone, as well as an antioxidant action which makes it very promising also for infertility” .
Finally, perhaps the least known but decisive compound is silymarin extracted from milk thistle. “It has been shown to inhibit the growth of prostate cancer cells and delay tumor progression, but also to reduce urinary symptoms and the PSA level in patients with benign prostatic hypertrophy. Silymarin – concludes Palmieri – also has hypocholesterolemic and hepatoprotective: thus completing the profile of a nutraceutical in which all the components contribute to inhibiting inflammatory and oxidative processes while at the same time amplifying organ protection mechanisms. Characteristics that make the new supplement a health option for all healthy men who want to maintain their sexual and general well-being for a long time.”